Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension | Science

May Be Interested In:Trump says he will appoint himself chair of Kennedy Center




Vascular inflammation regulates endothelial pathophenotypes, particularly in pulmonary arterial hypertension (PAH). Dysregulated lysosomal activity and cholesterol metabolism activate pathogenic inflammation, but their relevance to PAH is unclear. …

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